Description

1-(2-Hydroxyethyl)-4-(Chloropropyl)Piperazine Hydrochloride is a high-purity, functionalized piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of active pharmaceutical ingredients (APIs) and other specialty chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific piperazine-based functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various therapeutic agents, including potential candidates for central nervous system (CNS) drugs, anti-infectives, and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides where the piperazine moiety contributes to biological activity.
• Ligand and Catalyst Preparation: Employed in the creation of specialized ligands for metal catalysis and in the development of phase-transfer catalysts.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for producing specialty polymers with tailored properties.
• Bioconjugation and Linker Chemistry: Utilized in the design of chemical linkers for bioconjugation applications in drug delivery systems and diagnostic reagents.
• Research & Development: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	1-(2-Hydroxyethyl)-4-(Chloropropyl)Piperazine Hydrochloride
CAS No.	118951-26-1
Molecular Formula	C9H20Cl2N2O
Molecular Weight	243.17 g/mol
Synonyms	4-(3-Chloropropyl)-1-(2-hydroxyethyl)piperazine hydrochloride; 1-(2-Hydroxyethyl)-4-(3-chloropropyl)piperazine HCl; N-(2-Hydroxyethyl)-N'-(3-chloropropyl)piperazine dihydrochloride; 2-[4-(3-Chloropropyl)piperazin-1-yl]ethanol hydrochloride; 1-Piperazineethanol, 4-(3-chloropropyl)-, hydrochloride; HE-CPPZ HCl
EINECS	Contact for details

Quality Control

Our 1-(2-Hydroxyethyl)-4-(Chloropropyl)Piperazine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.