Description

6-(Aminomethyl)Piperidin-2-One Hydrochloride is a high-purity organic salt, serving as a critical building block in advanced pharmaceutical synthesis. Its bifunctional structure, featuring both a primary amine and a lactam ring, makes it a versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting the central nervous system (CNS).
• Peptidomimetic Chemistry: Used to introduce constrained piperidinone scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in the development of novel herbicides and pesticides with specific mode-of-action profiles.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and biochemical studies in university and corporate research laboratories.

Basic Information

Product Name	6-(Aminomethyl)Piperidin-2-One Hydrochloride
CAS No.	118894-94-3
Molecular Formula	C6H13ClN2O
Molecular Weight	164.63 g/mol
Synonyms	2-Piperidinone, 6-(aminomethyl)-, hydrochloride; 6-(Aminomethyl)-2-piperidinone hydrochloride; 6-Aminomethyl-2-piperidinone HCl; 2-Oxo-6-piperidinemethylamine hydrochloride; 6-(Aminomethyl)piperidin-2-one HCl; (6-Oxo-1,6-dihydropyridin-2-yl)methanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 6-(Aminomethyl)Piperidin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.