Description

1-tert-Butyloxycarbonyl-4-Amino-Piperazine is a high-purity, protected piperazine derivative widely used as a critical building block in organic synthesis. Its primary value lies in providing a reactive amino group that is temporarily shielded by the Boc (tert-butoxycarbonyl) protecting group, enabling selective reactions in complex multi-step sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, including kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Peptide Chemistry: Used as a linker or spacer unit in solid-phase peptide synthesis (SPPS) and for constructing peptide mimetics.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: A versatile reagent for exploring new chemical entities and developing novel synthetic methodologies in academic and industrial R&D labs.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for metal catalysis and organocatalysts.
• Polymer Modification: Can be used to introduce functional amine groups into polymer backbones for creating specialty polymers with tailored properties.

Basic Information

Product Name	1-tert-Butyloxycarbonyl-4-Amino-Piperazine
CAS No.	118753-66-5
Molecular Formula	C9H19N3O2
Molecular Weight	201.27 g/mol
Synonyms	1-Boc-4-Aminopiperazine; 4-Amino-1-Boc-piperazine; tert-Butyl 4-aminopiperidine-1-carboxylate; 1-N-Boc-4-aminopiperazine; 4-Amino-1-(tert-butoxycarbonyl)piperazine; N-Boc-4-aminopiperazine; Boc-4-Aminopiperazine; Piperazine, 4-amino-1-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our 1-tert-Butyloxycarbonyl-4-Amino-Piperazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.