Description

(8)S-Hepe CAS NO 118492-81-2 is a specialized, high-purity eicosanoid derivative, specifically a hydroxyeicosapentaenoic acid (HEPE) regioisomer. This compound serves as a critical advanced biochemical research tool and a potential synthetic intermediate for bioactive lipid mediators. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) focused on inflammation, metabolic pathways, and lipidomics.

Application

• Biochemical Research: Used as a reference standard and analytical tool in lipidomics and metabolomics studies to understand eicosanoid signaling pathways.
• Inflammation & Immunology Studies: Investigated for its role as a precursor or metabolite in specialized pro-resolving mediator (SPM) biosynthesis related to inflammatory resolution.
• Pharmaceutical Development: Serves as a key synthetic intermediate or building block for the development of novel therapeutic agents targeting inflammatory diseases.
• Cell Signaling & Receptor Studies: Employed in in vitro and cell-based assays to study the biological activity and receptor interactions of oxylipins.
• Nutritional Science Research: Used in studies examining the metabolic fate and biological effects of ω-3 fatty acid derivatives.

Basic Information

Product Name	(8)S-Hepe
CAS No.	118492-81-2
Molecular Formula	C20H30O3
Molecular Weight	318.45 g/mol
Synonyms	8(S)-HEPE; 8S-Hydroxy-5Z,9E,11Z,14Z,17Z-eicosapentaenoic Acid; 8(S)-Hydroxy-5Z,9E,11Z,14Z,17Z-eicosapentaenoic Acid; 8S-HEPE; (8S)-Hydroxyeicosapentaenoic Acid; 8-Hydroxy-EPA; 8(S)-HETE (Note: This is a common but less specific synonym for the 5-series analog; context is key).
EINECS	Contact for details

Quality Control

Our (8)S-Hepe is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for reliable research outcomes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support research compliance with traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 90% (by weight)
Solubility	Soluble in ethanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.