Description

Piperazine, 1,4-Dihydroxy-2,2,5,6-Tetramethyl-, trans- (9Ci) is a specialized, high-purity piperazine derivative characterized by its unique tetramethyl-substituted, trans-dihydroxy structure. This compound matters as a critical chiral building block and intermediate in advanced organic synthesis, offering precise stereochemical control for complex molecule construction. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and sophisticated ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those requiring specific stereocenters.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with targeted activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands used in asymmetric catalysis.
• Fine Chemical Research: Employed in academic and industrial laboratories for the construction of complex natural products and specialty chemicals.
• Polymer Chemistry: Potential monomer or cross-linking agent for creating specialty polymers with specific functional groups.

Basic Information

Product Name	Piperazine, 1,4-Dihydroxy-2,2,5,6-Tetramethyl-, trans- (9Ci)
CAS No.	118176-39-9
Molecular Formula	C8H18N2O2
Molecular Weight	174.24 g/mol
Synonyms	trans-1,4-Dihydroxy-2,2,5,5-tetramethylpiperazine; 2,2,5,5-Tetramethyl-1,4-dihydroxypiperazine; 1,4-Dihydroxy-2,2,5,5-tetramethylpiperazine; 1,4-Dihydroxy-2,2,5,6-tetramethylpiperazine; trans-2,2,5,5-Tetramethylpiperazine-1,4-diol; Tetramethyl-DHP; TMDPO (common abbreviation)
EINECS	Contact for details

Quality Control

Our Piperazine, 1,4-Dihydroxy-2,2,5,6-Tetramethyl-, trans- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% trans-isomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.