Description

Umbelliferone + Bstfa CAS NO 118074-57-0 is a specialized chemical derivative combining the natural coumarin derivative umbelliferone with the silylating agent N,O-Bis(trimethylsilyl)trifluoroacetamide (BSTFA). This pre-derivatized reagent is critical for analytical workflows requiring sensitive and reliable detection of hydroxyl-containing compounds. It is primarily utilized by analytical chemists and researchers in pharmaceutical development, environmental testing, and metabolomics who require efficient sample preparation for gas chromatography-mass spectrometry (GC-MS) analysis.

Application

• GC-MS Sample Derivatization: Acts as a pre-mixed reagent for the silylation of hydroxyl, carboxyl, and amine groups in complex organic molecules to improve their volatility and thermal stability for GC-MS analysis.
• Pharmaceutical Metabolite Profiling: Used in the identification and quantification of drug metabolites and endogenous biomarkers in biological matrices.
• Natural Product Analysis: Facilitates the characterization of phenolic acids, flavonoids, and other polar compounds found in plant extracts and herbal medicines.
• Forensic and Toxicology Screening: Employed in the preparation of samples for the detection of drugs of abuse, poisons, and other small molecules in forensic investigations.
• Environmental Pollutant Detection: Aids in the analysis of trace-level environmental contaminants, such as phenols and endocrine disruptors, in water and soil samples.
• Food Safety and Flavor Chemistry: Supports the analysis of flavor compounds, additives, and potential contaminants in food and beverage products.

Basic Information

Product Name	Umbelliferone + Bstfa
CAS No.	118074-57-0
Molecular Formula	C19H29F3N2O5Si2
Molecular Weight	502.62 g/mol
Synonyms	7-Hydroxycoumarin BSTFA derivative; Umbelliferone BSTFA adduct; 7-[(Trimethylsilyl)oxy]-2H-chromen-2-one, mixed with N,O-Bis(trimethylsilyl)trifluoroacetamide; 7-Hydroxycoumarin, TMS derivative with BSTFA; Silylation reagent mixture; Derivatization reagent for GC; BSTFA-Umbelliferone complex
EINECS	Contact for details

Quality Control

Our Umbelliferone + Bstfa is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive analytical applications. Each lot undergoes rigorous testing, including purity assessment by chromatographic methods (HPLC/GC) and identity confirmation (IR, NMR). A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and moisture content is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere to prevent decomposition. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0% (Umbelliferone derivative)
BSTFA Content (GC)	Balance
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.