Description

Enantio-Paf (C16) is a high-purity, enantiomerically pure form of the potent platelet-activating factor (PAF) analog. This compound is critical for advanced pharmacological research and development, serving as a precise molecular tool for studying PAF receptor-mediated signaling pathways. It is essential for scientists and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on inflammation, immunology, and cardiovascular research where stereochemical purity is paramount.

Application

• Pharmacological Research: A key reference standard and agonist for studying PAF receptor (PAFR) function and signaling in vitro and in vivo.
• Drug Discovery & Development: Used in high-throughput screening (HTS) assays to identify and validate novel PAFR antagonists and anti-inflammatory agents.
• Biochemical Studies: Employed to investigate the role of PAF in cellular processes such as platelet aggregation, neutrophil activation, and anaphylaxis.
• Inflammation & Immunology Models: Essential for creating precise experimental models of inflammatory diseases to test therapeutic candidates.
• Academic Research: A vital tool in university and institutional labs for fundamental research in lipid mediator biology and receptor pharmacology.
• Quality Control & Analytical Standards: Serves as a certified reference material (CRM) for calibrating analytical instruments and validating methods in QC laboratories.

Basic Information

Product Name	Enantio-Paf (C16)
CAS No.	117985-57-6
Molecular Formula	C26H54NO7P
Molecular Weight	523.68 g/mol
Synonyms	(R)-C16-PAF; (R)-Platelet Activating Factor C16; 1-O-Hexadecyl-2-O-acetyl-sn-glycero-3-phosphocholine (R-enantiomer); Enantiomeric PAF C-16; (R)-PAF C-16; AGEPC C-16 (R-enantiomer); (R)-AGEPC C16; sn-3-Phosphocholine-1-O-hexadecyl-2-O-acetyl (R)
EINECS	Contact for details

Quality Control

Our Enantio-Paf (C16) is manufactured under strict quality management systems to ensure exceptional enantiomeric purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR for structural confirmation, and stringent purity assays. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic and moisture-sensitive; ensure the container is sealed in a dry environment after each use. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.