Description

(2S,5S)-5-Hydroxy-1,2-Piperidinedicarboxylic Acid 2-Methyl 1-Benzyl Ester is a high-purity chiral piperidine derivative, a crucial building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it an essential intermediate for constructing complex molecules with high enantiomeric purity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry and process research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, especially those targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Serves as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereocenters.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying enzyme mechanisms or biological pathways.
• Academic Research: Used in university and institutional labs for methodological development in organic and heterocyclic chemistry.

Basic Information

Product Name	(2S,5S)-5-Hydroxy-1,2-Piperidinedicarboxylic Acid 2-Methyl 1-Benzyl Ester
CAS No.	117836-26-7
Molecular Formula	C16H19NO6
Molecular Weight	321.33 g/mol
Synonyms	(2S,5S)-5-Hydroxypiperidine-1,2-dicarboxylic acid 2-methyl 1-benzyl ester; 1-Benzyl 2-methyl (2S,5S)-5-hydroxypiperidine-1,2-dicarboxylate; (2S,5S)-1-Benzyloxycarbonyl-5-hydroxy-2-piperidinecarboxylic acid methyl ester; (2S,5S)-1-Cbz-5-hydroxy-2-piperidinecarboxylic acid methyl ester; (2S,5S)-5-Hydroxy-N-Cbz-pipecolic acid methyl ester; Methyl (2S,5S)-1-[(benzyloxy)carbonyl]-5-hydroxypiperidine-2-carboxylate; (2S,5S)-5-Hydroxy-1-Cbz-pipecolate methyl ester
EINECS	Contact for details

Quality Control

Our production of (2S,5S)-5-Hydroxy-1,2-Piperidinedicarboxylic Acid 2-Methyl 1-Benzyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.