Description

Taccalonolide C CAS NO 117803-96-0 is a highly potent, microtubule-stabilizing natural product isolated from plants of the genus *Tacca*. This compound is of significant interest due to its unique mechanism of action, which differs from other well-known taxane-site binders, making it a valuable tool for biochemical research. It is primarily sought after by researchers in the fields of oncology, pharmacology, and chemical biology for investigating novel cancer therapeutics and cellular mechanisms.

Application

• Biomedical Research: As a critical reference standard and active pharmaceutical ingredient (API) in studies focused on microtubule dynamics and cell cycle disruption.
• Anticancer Agent Development: Used in preclinical research to explore its efficacy and mechanism against various cancer cell lines, including multi-drug resistant phenotypes.
• Pharmacology & Toxicology: Employed in structure-activity relationship (SAR) studies to design and synthesize novel analogs with improved therapeutic profiles.
• Biochemical Assays: Serves as a precise tool in high-throughput screening and target validation assays within drug discovery pipelines.
• Academic Research: Utilized in university and institutional labs for fundamental research in cell biology and natural product chemistry.

Basic Information

Product Name	Taccalonolide C
CAS No.	117803-96-0
Molecular Formula	C34H46O10
Molecular Weight	614.73 g/mol
Synonyms	Taccalonolide C; (1S,2R,4aS,6aS,7S,8S,8aR,9S,10aS,10bS)-1,2,4a,7,8,9,10a,10b-Octahydro-8,9-dihydroxy-1,6a,8-trimethyl-11-oxo-6H-2,8a-methanocyclohepta[cd]inden-7-yl (2E)-2-methyl-2-butenoate; NSC 777751; Taccaoside aglycone derivative
EINECS	Contact for details

Quality Control

Our Taccalonolide C is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.