Description

6-Bromo-n-Methylimidazo[1,2-A]Pyrazin-8-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its brominated heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for oncology, antiviral, and central nervous system (CNS) applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted small-molecule therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized imidazopyrazine motifs into larger molecules.
• Biochemical Tool Compound: Potential use in developing probes for studying biological pathways and enzyme functions in academic and industrial R&D.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.

Basic Information

Product Name	6-Bromo-n-Methylimidazo[1,2-A]Pyrazin-8-Amine
CAS No.	117718-85-1
Molecular Formula	C7H7BrN4
Molecular Weight	227.06 g/mol
Synonyms	6-Bromo-8-amino-N-methylimidazo[1,2-a]pyrazine; 6-Bromo-8-methylaminoimidazo[1,2-a]pyrazine; 6-Bromo-N-methylimidazo[1,2-a]pyrazin-8-amine; 8-Amino-6-bromo-N-methylimidazo[1,2-a]pyrazine; Imidazo[1,2-a]pyrazin-8-amine, 6-bromo-N-methyl-; 117718-85-1
EINECS	Contact for details

Quality Control

Our 6-Bromo-n-Methylimidazo[1,2-A]Pyrazin-8-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.