Description

14-Iodo-15-Hydroxy-5,8,11-Eicosatrienoic Acid is a specialized iodinated eicosatrienoic acid derivative, a key intermediate in the synthesis of bioactive lipid mediators and analogs. This compound is valued for its role in biochemical research, particularly in studying the structure-activity relationships of eicosanoids and their impact on cellular signaling pathways. It is primarily utilized by research institutions and pharmaceutical development teams focused on inflammation, cardiovascular research, and novel lipid-based therapeutic agents.

Application

• Biochemical Research Intermediate: A critical building block for the synthesis of novel eicosanoid analogs and labeled tracers for metabolic studies.
• Pharmaceutical R&D: Used in the discovery and development of new anti-inflammatory and cardioprotective drug candidates targeting lipid pathways.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in lipidomics and analytical laboratories.
• Mechanistic Studies: Employed to investigate the biological functions and receptor interactions of iodinated fatty acid derivatives in cell culture and in vitro assays.
• Probe Development: Useful for creating molecular probes to study enzyme activity, such as lipoxygenases and cyclooxygenases, within complex biological systems.

Basic Information

Product Name	14-Iodo-15-Hydroxy-5,8,11-Eicosatrienoic Acid
CAS No.	117675-23-7
Molecular Formula	C₂₀H₃₁IO₃
Molecular Weight	446.36 g/mol
Synonyms	14-Iodo-15-HETE; 14-Iodo-15-hydroxy-5Z,8Z,11Z-eicosatrienoic acid; 14-I-15-HETE; 14-Iodo-15(S)-HETE; 14-I-15(S)-HETE; 15-Hydroxy-14-iodo-5,8,11-eicosatrienoic acid; Iodo-HETE; 14-Iodo-15-hydroxy-5,8,11-eicosatrienoic acid (mixed isomers)
EINECS	Contact for details

Quality Control

Our 14-Iodo-15-Hydroxy-5,8,11-Eicosatrienoic Acid is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for advanced research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles for the production of research-grade biochemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. The product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.