Description

2H-1,2-Benzoxazine-2-Carbonyl Chloride, 3,5,6,7,8,8A-Hexahydro- (9Ci) is a specialized heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. Its core value lies in the carbonyl chloride functional group, which enables efficient coupling reactions for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) or anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic core for bioactivity.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, or coatings with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic systems via amide bond formation or other nucleophilic acyl substitution reactions.
• Chemical Biology Probe Development: Utilized to create labeled compounds or affinity probes for studying biological targets and mechanisms of action.

Basic Information

Item	Detail
Product Name	2H-1,2-Benzoxazine-2-Carbonyl Chloride, 3,5,6,7,8,8A-Hexahydro- (9Ci)
CAS No.	117593-00-7
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	3,5,6,7,8,8a-Hexahydro-2H-1,2-benzoxazine-2-carbonyl chloride; Hexahydro-2H-1,2-benzoxazine-2-carbonyl chloride; 2H-1,2-Benzoxazine-2-carbonyl chloride, hexahydro-; 2-Oxo-3,5,6,7,8,8a-hexahydro-2H-1,2-benzoxazine-2-carbonyl chloride; Tetrahydro-2H-1,2-benzoxazine-2-carbonyl chloride (related); 1,2-Benzoxazine-2-carbonyl chloride, 3,4,5,6,7,8-hexahydro-
EINECS	Contact for details

Quality Control

Our production of 2H-1,2-Benzoxazine-2-Carbonyl Chloride adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.