Description

Calcium Dobesilate Monohydrate is a well-defined pharmaceutical active ingredient and chemical intermediate. This compound is valued for its specific biological activity and consistent quality, making it a critical component in the development and production of therapeutic formulations. It is primarily required by manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for producing finished dosage forms and conducting research.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of medications, particularly for vascular disorders.
• Vasoactive Drug Production: Key raw material in the manufacture of drugs used to treat chronic venous insufficiency and diabetic retinopathy.
• Intermediate for Chemical Synthesis: Used in the synthesis of more complex organic molecules and derivatives in research settings.
• Biochemical Research: Employed in laboratory studies to investigate its mechanism of action and pharmacokinetic properties.
• Reference Standard: Serves as a high-purity standard for quality control and analytical method development in pharmaceutical labs.
• Veterinary Pharmaceutical Applications: Potential use in developing treatments for similar vascular conditions in animals.

Basic Information

Product Name	Calcium Dobesilate Monohydrate
CAS No.	117552-78-0
Molecular Formula	C12H10CaO10S2 • H2O
Molecular Weight	436.42 g/mol (Monohydrate)
Synonyms	Calcium dobesilate monohydrate; Dobesilate Calcium Monohydrate; 2,5-Dihydroxybenzenesulfonic acid calcium salt monohydrate; Doxium; Doxi-OM; Doxium calcium; Calcium 2,5-dihydroxybenzenesulfonate monohydrate
EINECS	Contact for details

Quality Control

Our Calcium Dobesilate Monohydrate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing key parameters such as assay, related substances, and residual solvents. We can support compliance with various pharmacopoeial standards, including USP and EP, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	3.5% - 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.