Description

5-Methoxy-3,6-Dibenzylpyrazin-2(1H)-One 4-Oxide is a specialized heterocyclic compound featuring a pyrazinone core with benzyl and methoxy substituents, which is further modified as an N-oxide. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, particularly those targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and development of new herbicides or fungicides, leveraging its heterocyclic core.
• Chemical Synthesis Building Block: Employed in organic synthesis for the construction of complex, nitrogen-containing heterocycles.
• Academic & Institutional Research: Utilized in universities and research institutes for studying N-oxide chemistry and reaction mechanisms.

Basic Information

Product Name	5-Methoxy-3,6-Dibenzylpyrazin-2(1H)-One 4-Oxide
CAS No.	117333-12-7
Molecular Formula	C20H18N2O3
Molecular Weight	334.37 g/mol
Synonyms	5-Methoxy-3,6-dibenzylpyrazin-2(1H)-one 4-oxide; 3,6-Dibenzyl-5-methoxy-1H-pyrazin-2-one 4-oxide; 5-Methoxy-3,6-dibenzyl-1,2-dihydropyrazin-2-one 4-oxide; 1H-Pyrazin-2-one, 5-methoxy-3,6-dibenzyl-, 4-oxide; DBMPO (abbreviation); CAS 117333-12-7
EINECS	Contact for details

Quality Control

Our production of 5-Methoxy-3,6-Dibenzylpyrazin-2(1H)-One 4-Oxide adheres to stringent in-process controls and final batch testing to ensure high purity and consistent quality. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting cGMP-compliant development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.