Description

Bicyclo[2.2.2]Octane-1-Carbonyl Fluoride, 4-Methoxy- (9Ci) is a specialized fluorinated building block characterized by its rigid bicyclic framework. This compound matters for its role as a key intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals where its unique steric and electronic properties are leveraged. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a rigid, three-dimensional scaffold for enhanced biological activity or metabolic stability.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides, where the bicyclo[2.2.2]octane core can impart favorable physicochemical properties.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and advanced materials with tailored thermal and mechanical characteristics.
• Fluorination Chemistry: Employed as a reagent to introduce the carbonyl fluoride moiety into target molecules, a valuable transformation in medicinal and process chemistry.
• Ligand and Catalyst Development: Utilized for constructing sophisticated ligand systems for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new chemical space in synthetic organic chemistry laboratories.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.2]Octane-1-Carbonyl Fluoride, 4-Methoxy- (9Ci)
CAS No.	116935-81-0
Molecular Formula	C10H13FO2
Molecular Weight	184.21 g/mol
Synonyms	4-Methoxybicyclo[2.2.2]octane-1-carbonyl fluoride; 1-(Fluoroformyl)-4-methoxybicyclo[2.2.2]octane; 4-Methoxy-1-bicyclo[2.2.2]octanecarbonyl fluoride; Bicyclo[2.2.2]octane-1-carbonyl fluoride, 4-methoxy-; 4-Methoxybicyclo[2.2.2]octanecarboxylic acid fluoride
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octane-1-Carbonyl Fluoride, 4-Methoxy- (9Ci) is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its sensitivity to fluoride/strong alkali conditions, keep away from incompatible materials. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.