Description

(2S,5Sr)-(+)-2,5-Dihydro-3,6-Dimethoxy-2-Isopropyl-5-Methylpyrazine is a high-purity chiral compound valued for its role as a key flavoring agent and synthetic intermediate. Its distinct stereochemistry and methoxy-substituted pyrazine structure are critical for imparting specific roasted, nutty, or earthy flavor notes. This product is essential for flavor and fragrance manufacturers, as well as researchers in organic synthesis and pharmaceutical development requiring a specific enantiomer for chiral pool synthesis.

Application

• Flavor & Fragrance Industry: As a potent flavoring agent to create or enhance roasted, nutty, coffee, cocoa, or earthy flavor profiles in food, beverages, and savory applications.
• Synthetic Chemistry: Serves as a valuable chiral building block or intermediate in the asymmetric synthesis of more complex molecules, particularly in pharmaceutical research.
• Food Technology: Used in the development of process flavors and reaction flavors to replicate authentic cooked or roasted taste experiences.
• Aroma Chemicals: A key component in the formulation of sophisticated perfumes and fine fragrances requiring warm, gourmand, or tobacco-like notes.
• Research & Development: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) of pyrazine derivatives and their organoleptic properties.
• Standards & Reference Materials: Used as a certified reference standard for quality control and analytical method development in flavor analysis laboratories.

Basic Information

Product Name	(2S,5Sr)-(+)-2,5-Dihydro-3,6-Dimethoxy-2-Isopropyl-5-Methylpyrazine
CAS No.	116907-51-8
Molecular Formula	C10H18N2O2
Molecular Weight	198.26 g/mol
Synonyms	(+)-2,5-Dihydro-3,6-dimethoxy-2-isopropyl-5-methylpyrazine; (2S,5S)-2,5-Dihydro-3,6-dimethoxy-2-isopropyl-5-methylpyrazine; 2-Isopropyl-5-methyl-3,6-dimethoxy-2,5-dihydropyrazine; (S,S)-2,5-Dihydro-3,6-dimethoxy-2-isopropyl-5-methylpyrazine; Flavoring pyrazine derivative; 2,5-Dihydro-3,6-dimethoxy-2-(1-methylethyl)-5-methylpyrazine; (2S,5S)-2-(Propan-2-yl)-5-methyl-3,6-dimethoxy-2,5-dihydropyrazine
EINECS	Contact for details

Quality Control

Our (2S,5Sr)-(+)-2,5-Dihydro-3,6-Dimethoxy-2-Isopropyl-5-Methylpyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]	Contact for details
Refractive Index	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.