Description

p-Xylene-Alpha,Alpha'-13C2 is a stable isotope-labeled analog of p-xylene, where two specific carbon atoms are replaced with the carbon-13 isotope. This compound is essential for advanced analytical and research applications where precise molecular tracing and quantification are required. It is primarily used by scientists and quality control professionals in pharmaceutical research, metabolic studies, environmental analysis, and as an internal standard in quantitative NMR and mass spectrometry.

Application

• Internal Standard for Quantitative Analysis: Used in GC-MS, LC-MS, and NMR spectroscopy for accurate quantification of p-xylene and related compounds in complex matrices.
• Metabolic Pathway Tracing: Employed in biochemical and pharmacological research to study the metabolism and fate of xylene derivatives in biological systems.
• Environmental Analysis: Serves as a labeled standard for monitoring and quantifying p-xylene contamination in air, water, and soil samples.
• Polymer and Material Science Research: Used in mechanistic studies of polymerization processes and the synthesis of specifically labeled polymers.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradation products in drug substances.
• Isotope Dilution Mass Spectrometry (IDMS): A critical component in high-precision analytical methods requiring the utmost accuracy.

Basic Information

Product Name	p-Xylene-Alpha,Alpha'-13C2
CAS No.	116598-94-8
Molecular Formula	C613C2H10 or C8H10 (with two 13C atoms)
Molecular Weight	108.13 g/mol (approx., based on 13C enrichment)
Synonyms	1,4-Dimethylbenzene-alpha,alpha'-13C2; p-Xylene-13C2 (ring labeled); 13C2-p-Xylene; 4-Methyltoluene-13C2; p-Xylene (13C labeled); Para-xylene-13C2; [13C2]-p-Xylene; Labeled p-Xylene
EINECS	Contact for details

Quality Control

Every batch of p-Xylene-Alpha,Alpha'-13C2 is produced and analyzed under strict quality protocols to ensure isotopic and chemical purity meets the exacting standards of analytical research. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic enrichment (atom % 13C), chemical purity (by GC), and identity confirmation. Our quality system is designed to support GMP/GLP-compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat, sparks, and open flame. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Enrichment (atom % 13C)	≥ 99% (on labeled positions)
Chemical Purity (GC)	≥ 98.0%
Isotopic Purity (by MS)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.