Description

5-Chloro-6-Nitro-1,3-Benzoxazole is a high-purity, synthetically valuable heterocyclic building block. This compound is a key intermediate in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its reactive nitro and chloro substituents on the benzoxazole core.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobial compounds.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Building Block: Serves as a versatile scaffold in academic and industrial research for constructing more complex heterocyclic systems and functional materials.
• Material Science Research: Investigated for potential use in the development of organic semiconductors, dyes, and photoactive materials due to its electron-deficient aromatic system.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	5-Chloro-6-Nitro-1,3-Benzoxazole
CAS No.	116549-11-2
Molecular Formula	C7H3ClN2O3
Molecular Weight	198.56 g/mol
Synonyms	5-Chloro-6-nitrobenzoxazole; 1,3-Benzoxazole, 5-chloro-6-nitro-; 6-Nitro-5-chloro-1,3-benzoxazole; 5-Chloro-6-nitrobenzo[d]oxazole; 5-Chloro-6-nitro-BZO
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Nitro-1,3-Benzoxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.