Description

2-Bromo-6-Chlorobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce both bromo and chloro substituents in a single, reactive functional group, enabling efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring specific halogenated benzoyl motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the 2-bromo-6-chloro substitution pattern confers specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of novel organic electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and R&D Laboratories: Used in research for method development and exploring new chemical entities in medicinal chemistry.

Basic Information

Product Name	2-Bromo-6-Chlorobenzoyl Chloride
CAS No.	116529-65-8
Molecular Formula	C7H3BrCl2O
Molecular Weight	253.91 g/mol
Synonyms	2-Bromo-6-chlorobenzoic acid chloride; 6-Chloro-2-bromobenzoyl chloride; Benzoic acid, 2-bromo-6-chloro-, chloride; (2-Bromo-6-chlorophenyl)(oxo)methane; 2-Bromo-6-chlorobenzenecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Chlorobenzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.