Description

Vapreotide Acetate is a synthetic, cyclic octapeptide analog of somatostatin, formulated as its acetate salt for enhanced stability. This compound is a potent inhibitor of growth hormone, glucagon, and insulin secretion, making it a critical active pharmaceutical ingredient (API) for therapeutic development. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on endocrinology and oncology. Its targeted mechanism of action supports advanced drug formulations for specific medical conditions.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable formulations for therapeutic applications.
• Endocrine Disorder Research: Investigation and development of treatments for acromegaly and related growth hormone disorders.
• Oncological Research: Study of its anti-secretory properties in the management of symptoms from neuroendocrine tumors (NETs).
• Gastrointestinal Research: Exploration of its use in treating severe diarrheal conditions, such as those associated with carcinoid syndrome.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in laboratories.
• Peptide Chemistry Studies: Used as a model compound in advanced peptide synthesis and stability research.

Basic Information

Product Name	Vapreotide Acetate
CAS No.	116430-60-5
Molecular Formula	C57H70N14O10S2 • xC2H4O2
Molecular Weight	1131.4 g/mol (free base)
Synonyms	RC-160; BIM-23014; Vapreotide; [D-β-Nal1,Cys2,Tyr3,D-Trp4,Lys5,Cys6,Val-NH27]Somatostatin-14; Somatuline (referring to the brand name drug containing vapreotide); Octapeptide Somatostatin Analog; Cyclo(N-β-naphthylalanyl-cysteinyl-tyrosyl-D-tryptophyl-lysyl-valinyl-cysteinyl)trifluoroacetate (alternate salt form)
EINECS	Contact for details

Quality Control

Our Vapreotide Acetate is manufactured under strict quality systems to ensure it meets the high standards required for pharmaceutical development. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and assay, determination of related substances, residual solvents, and identity confirmation. A Certificate of Analysis (COA) documenting full compliance with agreed specifications is provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the product should be stored under controlled room temperature conditions (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C. Keep the container sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH limits
Acetate Content (HPLC/IC)	5.0% - 12.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.