Description

2-((4Ar,4Bs,6As,7S,9As,9Bs)-4A,6A-Dimethyl-2-Oxohexadecahydro-1H-Indeno[5,4-F]Quinoline-7-Carboxamido)-2-Methylpropanoic Acid is a high-purity, complex organic compound with a defined stereochemistry, serving as a critical advanced intermediate in pharmaceutical synthesis. Its value lies in enabling the production of sophisticated active pharmaceutical ingredients (APIs) with precise structural and chiral requirements. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries, particularly those focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules, particularly in the development of new chemical entities (NCEs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of targeted compound libraries.
• Process Chemistry: Serves as a pivotal intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing.
• Chiral Synthesis: Its defined stereocenters make it valuable for the synthesis of enantiomerically pure compounds, crucial for modern drug development.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals requiring complex molecular architectures.

Basic Information

Product Name	2-((4Ar,4Bs,6As,7S,9As,9Bs)-4A,6A-Dimethyl-2-Oxohexadecahydro-1H-Indeno[5,4-F]Quinoline-7-Carboxamido)-2-Methylpropanoic Acid
CAS No.	116285-41-7
Molecular Formula	C23H36N2O4
Molecular Weight	404.55 g/mol
Synonyms	2-((4Ar,4Bs,6As,7S,9As,9Bs)-4A,6A-Dimethyl-2-Oxododecahydro-1H-Indeno[5,4-F]Quinoline-7-Carboxamido)-2-Methylpropanoic Acid; (4Ar,4Bs,6As,7S,9As,9Bs)-7-[(2-Carboxy-1,1-Dimethylethyl)Carbamoyl]-4A,6A-Dimethyl-4A,4B,5,6,6A,7,8,9,9A,9B,10,11-Dodecahydro-1H-Indeno[5,4-F]Quinolin-2-One; 2-[(4Ar,4Bs,6As,7S,9As,9Bs)-4A,6A-Dimethyl-2-Oxododecahydro-1H-Indeno[5,4-F]Quinolin-7-Ylcarboxamido]-2-Methylpropanoic Acid; 2-[(4Ar,4Bs,6As,7S,9As,9Bs)-4A,6A-Dimethyl-2-Oxo-1,3,4,4A,4B,5,6,6A,7,8,9,9A,9B,10,11,11A-Hexadecahydroindeno[5,4-F]Quinolin-7-Ylcarboxamido]-2-Methylpropanoic Acid
EINECS	Contact for details

Quality Control

Our 2-((4Ar,4Bs,6As,7S,9As,9Bs)-4A,6A-Dimethyl-2-Oxohexadecahydro-1H-Indeno[5,4-F]Quinoline-7-Carboxamido)-2-Methylpropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.