Description

1,2-Dimyristoyl-3-Eicosapentaenoyl-Rac-Glycerol CAS NO 116198-40-4 is a structured triglyceride (TAG) where the sn-1 and sn-2 positions are esterified with myristic acid (C14:0) and the sn-3 position is esterified with eicosapentaenoic acid (EPA, C20:5). This specific molecular architecture is engineered to deliver the metabolic and nutritional benefits of ω-3 fatty acids in a highly bioavailable and stable lipid form. It is a critical advanced intermediate for researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced lipid-based drug delivery sectors, particularly for developing specialized parenteral nutrition emulsions and bioactive lipid formulations.

Application

• Pharmaceutical Research & Development: As a key synthetic intermediate for creating novel structured lipids with targeted metabolic effects.
• Parenteral Nutrition: A potential component in next-generation intravenous lipid emulsions designed to modulate immune response and provide essential fatty acids.
• Nutraceutical Formulations: For the development of high-purity, specialty dietary supplements aimed at delivering concentrated EPA in a structured triglyceride format for enhanced bioavailability.
• Lipid Nanoparticle (LNP) Systems: Used in the engineering of advanced drug delivery carriers, including those for mRNA and other nucleic acid therapeutics, where specific lipid composition dictates stability and efficacy.
• Biochemical & Metabolic Studies: Serves as a standard or substrate in research investigating lipid metabolism, enzyme specificity (e.g., lipases), and membrane biophysics.
• Cosmeceuticals: Potential ingredient in high-end skincare formulations for its lipid-restructuring and barrier-support properties.

Basic Information

Product Name	1,2-Dimyristoyl-3-Eicosapentaenoyl-Rac-Glycerol
CAS No.	116198-40-4
Molecular Formula	C49H84O6
Molecular Weight	769.2 g/mol
Synonyms	1,2-Ditetradecanoyl-3-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-rac-glycerol; EPA-Myristin Structured Triglyceride; Glycerol, 1,2-dimyristoyl-3-(5,8,11,14,17-eicosapentaenoyl)-, rac-; TAG (14:0/14:0/20:5); 1,2-Di-O-tetradecanoyl-3-O-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycerol (racemic); MM-EPA Triglyceride; Myristic Acid-EPA Structured Lipid
EINECS	Contact for details

Quality Control

Our 1,2-Dimyristoyl-3-Eicosapentaenoyl-Rac-Glycerol is produced under strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and consistency suitable for research and cGMP manufacturing applications. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, fatty acid profile, and impurity limits. Specifications can be aligned with client requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Fatty Acid Composition (GC)	Myristic Acid (C14:0): ~65-70% Eicosapentaenoic Acid (C20:5): ~30-35%
Peroxide Value	≤ 5.0 meq/kg
Acid Value	≤ 1.0 mg KOH/g
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.