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1,2-Dioleoyl-3-Docosohexaenoyl-Rac-Glycerol CAS NO 116198-39-1


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CAS No.:116198-39-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dioleoyl-3-Docosohexaenoyl-Rac-Glycerol is a structured triglyceride (TAG) where the glycerol backbone is esterified with two oleic acid (C18:1) residues and one docosahexaenoic acid (DHA, C22:6) residue. This specific molecular architecture is critical for advanced research and development in lipid-based delivery systems and nutritional science. It is primarily utilized by researchers and formulators in the pharmaceutical, nutraceutical, and specialty chemical industries seeking to leverage the unique properties of structured lipids for enhanced bioavailability and targeted functionality.

Application

  • Pharmaceutical Excipient: As a key component in lipid nanoparticle (LNP) formulations for the encapsulation and delivery of sensitive active pharmaceutical ingredients (APIs), including mRNA and siRNA.
  • Nutraceutical Ingredient: Used in the development of high-end dietary supplements and medical nutrition products designed to deliver DHA in a structured, metabolically favorable form.
  • Biochemical Research: Serves as a standard or substrate in lipidomics research, enzymatic studies (e.g., lipase specificity), and investigations into lipid metabolism and membrane biophysics.
  • Cosmetic Formulations: Incorporated into premium skincare products for its emollient properties and potential skin-barrier benefits.
  • Model Lipid System: Employed in the creation of synthetic membranes and vesicles to study lipid-lipid and lipid-protein interactions.
  • Food Science: Investigated for use in functional food products aimed at improving the stability and delivery of ω-3 fatty acids.

Basic Information

Product Name 1,2-Dioleoyl-3-Docosohexaenoyl-Rac-Glycerol
CAS No. 116198-39-1
Molecular Formula C65H108O6
Molecular Weight 985.55 g/mol
Synonyms 1,2-Dioleoyl-3-docosahexaenoyl-rac-glycerol; DHA-rich Triglyceride; TAG 18:1/18:1/22:6; Glycerol, 1,2-dioleoyl-3-docosahexaenoyl-, rac-; Structured Lipid (OO-DHA); 1,2-Di-O-oleoyl-3-O-docosahexaenoyl-rac-glycerol; (rac)-1,2-Dioleoyl-3-docosahexaenoylglycerol
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and formulation. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and fatty acid composition. Certificates of Analysis (COA) detailing specific batch results are available upon request. We adhere to strict quality management protocols to ensure supply reliability and product consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to reach room temperature in a desiccator before opening to minimize moisture condensation. Keep away from heat and oxidizing agents.

Specification

Item Specification
Appearance Colorless to pale yellow oil
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Fatty Acid Composition (GC) Oleic Acid (C18:1): ~65-70% Docosahexaenoic Acid (C22:6): ~30-35%
Peroxide Value < 5.0 meq/kg
Acid Value < 1.0 mg KOH/g
Water Content (KF) < 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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