Description

(3S,4R)-4-Phenylpyrrolidin-3-Amine is a high-purity chiral amine building block of significant importance in modern synthetic chemistry. Its defined stereochemistry makes it a critical intermediate for the development of enantiomerically pure pharmaceuticals and bioactive compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate a rigid, functionalized pyrrolidine scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalyst Ligand Precursor: Used in the development of novel chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating advanced, stereospecific active ingredients for crop protection.
• Fine Chemical Production: Employed in the multistep synthesis of complex natural products, flavors, and fragrances requiring high stereochemical fidelity.
• Academic & R&D: A valuable compound for methodological studies in organic synthesis and medicinal chemistry within research institutions.
• Peptidomimetics: The pyrrolidine core is utilized in designing conformationally constrained peptide analogs for therapeutic applications.

Basic Information

Product Name	(3S,4R)-4-Phenylpyrrolidin-3-Amine
CAS No.	116169-51-8
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	(3S,4R)-3-Amino-4-phenylpyrrolidine; 4-Phenyl-3-pyrrolidinamine, (3S,4R)-; (3S,4R)-4-Phenyl-3-pyrrolidinamine; (3S,4R)-1,2,3,6-Tetrahydropyridin-3-amine (tautomeric form); 4-Phenylpyrrolidin-3-amine, (3S,4R)-; (3S,4R)-4-Phenyl-3-aminopyrrolidine; (3S,4R)-4-Phenylpyrrolidin-3-ylamine; 116169-51-8
EINECS	Contact for details

Quality Control

Our (3S,4R)-4-Phenylpyrrolidin-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.