Description

2-(Fluoromethyl)Piperazine Dihydrochloride is a high-purity, fluorinated piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical candidates and agrochemicals, where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. It is primarily utilized by research institutions and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to explore fluorinated analogs.
• Agrochemical Synthesis: Serves as a precursor in the development of new-generation herbicides and fungicides with enhanced efficacy.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis and metal complexation.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A requested material for bespoke chemical synthesis services targeting niche applications.

Basic Information

Product Name	2-(Fluoromethyl)Piperazine Dihydrochloride
CAS No.	116163-30-5
Molecular Formula	C5H12FCl2N2
Molecular Weight	199.07 g/mol
Synonyms	2-(Fluoromethyl)piperazine dihydrochloride; 1-(Fluoromethyl)piperazine dihydrochloride; Piperazine, 2-(fluoromethyl)-, dihydrochloride; 2-Fluoromethylpiperazine dihydrochloride; (Fluoromethyl)piperazine dihydrochloride; 116163-30-5; 2-Fluoromethyl-piperazine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Fluoromethyl)Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.