Description

3-Methylpiperidine-3-Carboxylic Acid is a versatile chiral piperidine derivative, a key building block in advanced organic synthesis. Its value lies in its unique bicyclic structure, which serves as a crucial scaffold for constructing complex molecules with high stereochemical control. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of central nervous system (CNS) drugs, receptor modulators, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its piperidine core.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and R&D: A valuable compound for medicinal chemistry research and process development in university and corporate laboratories.

Basic Information

Product Name	3-Methylpiperidine-3-Carboxylic Acid
CAS No.	116140-49-9
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	3-Methylnipecotic Acid; 3-Methyl-3-piperidinecarboxylic Acid; 3-Carboxy-3-methylpiperidine; 3-Methylpiperidine-3-carboxylic acid; 3-Methyl-3-piperidinecarboxylic acid; (+/-)-3-Methylnipecotic acid; 3-Methyl-3-piperidinecarboxylic acid, 3-Methylnipecotic acid
EINECS	Contact for details

Quality Control

Our 3-Methylpiperidine-3-Carboxylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.