Description

Dehydromiltirone is a bioactive diterpenoid quinone compound of significant interest in advanced pharmaceutical research and development. Its unique chemical structure makes it a valuable intermediate for synthesizing novel therapeutic agents and a key reference standard for analytical studies. This high-purity compound is primarily utilized by research institutions, pharmaceutical developers, and manufacturers of fine chemicals. Dehydromiltirone CAS NO 116064-77-8 is essential for projects requiring a reliable and well-characterized chemical entity.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and neurology research.
• Biochemical Research: Used as a reference standard and active agent in studies investigating cellular mechanisms, enzyme interactions, and signal transduction pathways.
• Analytical Standard: Employed as a high-purity calibrant in HPLC, LC-MS, and NMR for method development, validation, and quality control in laboratories.
• Natural Product Chemistry: Acts as a representative compound for the study of diterpenoid derivatives isolated from traditional medicinal plants like Salvia miltiorrhiza (Danshen).
• Preclinical Studies: Utilized in in vitro and in vivo models to evaluate pharmacological activities, including potential antioxidant and cytotoxic effects.
• Fine Chemical Synthesis: Provides a specialized starting material for the custom synthesis of complex molecules in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	Dehydromiltirone
CAS No.	116064-77-8
Molecular Formula	C19H18O3
Molecular Weight	294.35 g/mol
Synonyms	Dehydrotanshinone IIA; 1,6-Dimethyl-8,9-dihydro-7H-naphtho[5,6-g][1]benzofuran-6,11,12-trione; (R)-Dehydromiltirone; Dehydrotanshinone II; Danshenxinkun B; NSC 365798; 116064-77-8; Dehydromiltiron
EINECS	Contact for details

Quality Control

Every batch of Dehydromiltirone is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥98% (HPLC), suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and identification tests is provided with each shipment. We adhere to cGMP principles where applicable, and specifications can be aligned with client-specific pharmacopeial or internal standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Reddish-brown to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.