Description

1H-Pyrazolo[3,4-B]Pyrazin-3(2H)-One is a high-purity heterocyclic organic compound, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. This product is essential for research and development chemists and process scale-up teams within the global pharmaceutical, agrochemical, and specialty fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage its fused pyrazolo-pyrazine core structure.
• Material Science: Investigated as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Biochemical Tool Compound: Serves as a core scaffold for developing chemical probes and inhibitors used in biochemical and pharmacological research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyrazin-3(2H)-One
CAS No.	116056-01-0
Molecular Formula	C5H4N4O
Molecular Weight	136.11 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyrazin-3-ol; 3-Hydroxy-1H-pyrazolo[3,4-b]pyrazine; 1H-Pyrazolo[3,4-b]pyrazin-3(2H)-one; Pyrazolo[3,4-b]pyrazin-3-ol; 1,2-Dihydro-3H-pyrazolo[3,4-b]pyrazin-3-one; 3-Hydroxypyrazolo[3,4-b]pyrazine; 1H-Pyrazolo(3,4-b)pyrazin-3-ol
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyrazin-3(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.