Description

1-(2,4-Difluorophenyl)Piperazine is a high-purity, versatile fluorinated piperazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents, antidepressants, and antipsychotics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atoms for improved efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for metal catalysis and in the development of novel organocatalysts.
• Material Science Precursor: Acts as a monomer or functionalization agent in the synthesis of advanced polymers and specialty materials.

Basic Information

Product Name	1-(2,4-Difluorophenyl)Piperazine
CAS No.	115761-79-0
Molecular Formula	C10H12F2N2
Molecular Weight	198.21 g/mol
Synonyms	1-(2,4-Difluorophenyl)piperazine; 2,4-Difluorophenylpiperazine; N-(2,4-Difluorophenyl)piperazine; 1-(2,4-Difluorophenyl)-piperazine; 2,4-Difluoro-1-(piperazin-1-yl)benzene; 1-(2,4-Difluorophenyl)piperazine hydrochloride (salt form); 115761-79-0; Difluorophenylpiperazine
EINECS	Contact for details

Quality Control

Our 1-(2,4-Difluorophenyl)Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP, ICH Q7, and other relevant pharmaceutical and chemical industry standards for intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.