Description

(5R)-3-[[(Z)-2-(Acetylamino)Ethenyl]Thio]-7-Oxo-6α-[(S)-1-(Sulfooxy)Ethyl]-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid is a chemically advanced, semi-synthetic β-lactam compound. This molecule is of significant interest for its role as a key intermediate in the synthesis of novel cephalosporin antibiotics. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of advanced cephalosporin-class antibiotics.
• Antibacterial Research: Used in the research and development of new antibacterial compounds with potentially improved efficacy or spectrum of activity.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for the commercial production of active pharmaceutical ingredients (APIs).
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	(5R)-3-[[(Z)-2-(Acetylamino)Ethenyl]Thio]-7-Oxo-6α-[(S)-1-(Sulfooxy)Ethyl]-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid
CAS No.	115730-78-4
Molecular Formula	C14H18N2O8S2
Molecular Weight	406.43 g/mol
Synonyms	7β-[(Z)-2-(Acetylamino)-2-carboxyethenylthio]-7α-methoxy-3-[(1-methyl-1H-tetrazol-5-yl)thio]methyl-1-dethia-1-oxa-3-cephem-4-carboxylic Acid (related structure); Cephalosporin C-3' side chain derivative; 6α-(1-Sulfooxyethyl)penem intermediate; (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[(1Z)-2-(acetylamino)-1-[(sulfooxy)imino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid (tautomeric form); Antibiotic intermediate 115730-78-4.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We adhere to strict in-process controls and final release specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. Production can be aligned with cGMP guidelines for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.