Description

4-n-Boc-Amino-Piperidine-4-Carboxylic Acid Methyl Ester is a high-purity, protected piperidine derivative that serves as a critical building block in modern organic synthesis. This compound is essential for the efficient construction of complex molecules, offering a versatile scaffold for the introduction of functionalized piperidine rings. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Peptidomimetics & Constrained Peptides: Used to incorporate rigid, functionalized piperidine structures into peptide backbones to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study enzyme function and biological pathways.
• Agrochemical Research: Employed in the discovery and development of novel herbicides, fungicides, and insecticides.
• Ligand & Catalyst Development: Utilized in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring high-purity, advanced intermediates.

Basic Information

Product Name	4-n-Boc-Amino-Piperidine-4-Carboxylic Acid Methyl Ester
CAS No.	115655-44-2
Molecular Formula	C13H24N2O4
Molecular Weight	272.34 g/mol
Synonyms	Methyl 4-[(tert-Butoxycarbonyl)amino]piperidine-4-carboxylate; 4-[(tert-Butoxycarbonyl)amino]piperidine-4-carboxylic Acid Methyl Ester; 4-(Boc-amino)piperidine-4-carboxylic Acid Methyl Ester; 4-(tert-Butoxycarbonylamino)piperidine-4-carboxylic Acid Methyl Ester; 4-N-Boc-4-Piperidinecarboxylic Acid Methyl Ester; 1-Boc-4-amino-4-piperidinecarboxylic Acid Methyl Ester; Methyl 1-Boc-4-aminoisonipecotate; 4-Amino-1-Boc-piperidine-4-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 4-n-Boc-Amino-Piperidine-4-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to comprehensive in-house specifications, which typically include identity confirmation by spectroscopic methods (NMR, IR), purity assessment by HPLC, and control of specific impurities. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.