Description

1,4-Piperidinedicarboxylic Acid, 4-Amino-, 4-Methyl 1-(Phenylmethyl) Ester is a high-purity, functionalized piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active molecules. It is primarily required by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Building Block for Medicinal Chemistry: Used in the construction of piperidine-based scaffolds for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Research: Employed in the development of new pesticides and herbicides that require specific chiral or functionalized amine centers.
• Ligand Synthesis: Useful for creating novel ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial research quantities.

Basic Information

Product Name	1,4-Piperidinedicarboxylic Acid, 4-Amino-, 4-Methyl 1-(Phenylmethyl) Ester
CAS No.	115655-42-0
Molecular Formula	C16H22N2O4
Molecular Weight	306.36 g/mol
Synonyms	4-Amino-4-methyl-1-(phenylmethyl) piperidine-1,4-dicarboxylate; 4-Amino-4-methyl-1-benzyl piperidine-1,4-dicarboxylic acid ester; 1-Benzyl 4-methyl 4-amino-1,4-piperidinedicarboxylate; 4-Amino-1-benzyl-4-methyl piperidine-1,4-dicarboxylate; 1,4-Piperidinedicarboxylic acid, 4-amino-4-methyl-, 1-(phenylmethyl) ester; 4-Amino-4-methyl-1-benzyl ester of 1,4-piperidinedicarboxylic acid; Amino-methyl-benzyl piperidinedicarboxylate
EINECS	Contact for details

Quality Control

Our production of 1,4-Piperidinedicarboxylic Acid, 4-Amino-, 4-Methyl 1-(Phenylmethyl) Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. All materials are fully characterized, and Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with each shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.