Description

Pyrido[2,3-B]Pyrazine, 2-(Trifluoromethyl)- (9Ci) is a high-value, nitrogen-containing heterocyclic compound distinguished by its fused pyridine-pyrazine core and a strategically positioned trifluoromethyl group. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block in modern organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and antiviral therapies.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Acts as a sophisticated ligand scaffold in coordination chemistry for creating catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Precursor: Employed in the research of organic electronic materials, such as electron-transport layers in OLEDs or as a component in conductive polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Fluorinated Building Block: Provides a source of the -CF3 moiety for introducing fluorine into target molecules to modulate lipophilicity, bioavailability, and metabolic profile.

Basic Information

Product Name	Pyrido[2,3-B]Pyrazine, 2-(Trifluoromethyl)- (9Ci)
CAS No.	115652-65-8
Molecular Formula	C8H4F3N3
Molecular Weight	199.14 g/mol
Synonyms	2-(Trifluoromethyl)pyrido[2,3-b]pyrazine; 2-(Trifluoromethyl)-pyrido[2,3-b]pyrazine; Pyrido[2,3-b]pyrazine, 2-(trifluoromethyl)-; 115652-65-8; 2-Trifluoromethylpyrido[2,3-b]pyrazine; 2-CF3-Pyrido[2,3-b]pyrazine; 2-(Trifluoromethyl)-9H-pyrido[2,3-b]pyrazine
EINECS	Contact for details

Quality Control

Every batch of Pyrido[2,3-B]Pyrazine, 2-(Trifluoromethyl)- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.