Description

2,3,4-Trichloro-5-Fluorobenzoic Chloride is a highly reactive and versatile aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of halogen substituents, which enable precise functionalization for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a fluorinated and chlorinated benzoic acid core.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides where the halogen pattern confers specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Incorporated into polymer backbones or as a modifying agent to impart unique thermal, chemical, or surface properties to high-performance materials.
• Dyestuff and Pigment Manufacturing: Acts as an intermediate for producing complex, halogenated dyes and pigments with enhanced color fastness and stability.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic labs exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2,3,4-Trichloro-5-Fluorobenzoic Chloride
CAS No.	115549-05-8
Molecular Formula	C7HCl4FO
Molecular Weight	261.84 g/mol
Synonyms	2,3,4-Trichloro-5-fluorobenzoyl chloride; Benzoic acid, 2,3,4-trichloro-5-fluoro-, chloride; 5-Fluoro-2,3,4-trichlorobenzoic acid chloride; 2,3,4-Trichloro-5-fluorobenzoic acid chloride; 2,3,4-Trichloro-5-fluorobenzoylchloride; TCFBC
EINECS	Contact for details

Quality Control

Our 2,3,4-Trichloro-5-Fluorobenzoic Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP, ISO, and REACH standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure the container is kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as water, alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.