Description

19(S)-Hete is a specific stereoisomer of a hydroxyeicosatetraenoic acid (HETE), a bioactive lipid mediator derived from arachidonic acid. This compound matters for its role as a key signaling molecule in various physiological and pathological processes, particularly in inflammation and immune response regulation. It is needed by researchers in pharmaceutical development, biochemical research, and academic institutions for use as a reference standard, a biochemical tool, and in metabolic pathway studies.

Application

• Biochemical Research: Used as a high-purity reference standard for the study of eicosanoid pathways, lipid metabolism, and inflammatory mediators.
• Pharmaceutical R&D: Serves as a critical intermediate or analytical standard in the development of drugs targeting inflammation, asthma, and cardiovascular diseases.
• Cell Signaling Studies: Employed to investigate the specific biological effects and receptor interactions of the 19(S)-HETE stereoisomer in vitro and in vivo.
• Analytical Method Development: Used for calibrating equipment and validating methods in analytical techniques such as LC-MS, HPLC, and GC-MS for eicosanoid profiling.
• Academic Research: A vital tool for universities and research institutes exploring the nuanced roles of different HETE isomers in human physiology and disease models.

Basic Information

Product Name	19(S)-Hete
CAS No.	115461-40-0
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	19(S)-Hydroxyeicosatetraenoic acid; 19(S)-HETE; (5Z,8Z,11Z,14Z)-19-Hydroxyeicosa-5,8,11,14-tetraenoic acid; 19S-HETE; 19-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid; 19(S)-Hydroxyarachidonic acid
EINECS	Contact for details

Quality Control

Our 19(S)-Hete is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable and reproducible performance in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, solutions should be prepared in appropriate, anhydrous solvents and kept at -80°C. Allow the product to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95%
Purity (HPLC)	≥ 98% (Total Purity)
Stereochemical Purity	≥ 99% (19S isomer)
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.