Description

19(R)-Hete CAS NO 115461-39-7 is a specific stereoisomer of the hydroxyeicosatetraenoic acid (HETE) family, a class of bioactive lipid mediators derived from arachidonic acid. This compound is of significant interest in biochemical and pharmacological research due to its role as a specific ligand and modulator of various biological pathways. It serves as a critical reference standard and research tool for scientists in the pharmaceutical, biotechnology, and academic sectors investigating inflammation, cell signaling, and metabolic processes.

Application

• Biochemical Research: Used as a high-purity reference standard in analytical methods such as HPLC and LC-MS for the quantification of eicosanoids in biological samples.
• Pharmacological Studies: Employed to investigate the role of specific HETE isomers in inflammatory pathways, receptor binding studies, and signal transduction mechanisms.
• Drug Discovery & Development: Serves as a key intermediate or biological target molecule in the development of novel anti-inflammatory and metabolic disorder therapeutics.
• Cell Biology: Applied in in vitro cell culture studies to elucidate the effects of lipid mediators on cell proliferation, differentiation, and apoptosis.
• Diagnostic Development: Utilized in the development and calibration of immunoassays and diagnostic kits targeting specific lipid metabolites.

Basic Information

Product Name	19(R)-Hete
CAS No.	115461-39-7
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	19(R)-Hydroxyeicosatetraenoic acid; 19(R)-HETE; (19R)-HETE; 19R-HETE; 19(R)-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid; 19R-Hydroxyarachidonic acid; 19-HETE (R-isomer); 19(R)-HETE reference standard
EINECS	Contact for details

Quality Control

Every batch of 19(R)-Hete is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chromatographic purity analysis and spectroscopic identification, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results for identity, assay, and impurities is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Store away from strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or film
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Area %)
Isomeric Purity (Chiral HPLC)	≥ 98% (19R-isomer)
Solubility	Soluble in ethanol, DMSO, and dimethyl formamide

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.