Description

2-Azetidinone,3-Amino-4-(2-Hydroxyethyl)-,(3S-Cis)-(9Ci) is a high-purity, stereochemically defined azetidinone derivative, a crucial advanced intermediate in modern pharmaceutical synthesis. This compound matters for its role as a key chiral building block in the development of novel β-lactam antibiotics and other biologically active molecules. Pharmaceutical R&D teams and fine chemical manufacturers need this material for creating next-generation therapeutics with enhanced efficacy and specificity.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel β-lactam antibiotics, including carbapenems and penems.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing complex molecular scaffolds in drug discovery programs targeting bacterial infections.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) in pilot plants and commercial manufacturing.
• Bioconjugation & Prodrug Synthesis: The amino and hydroxyethyl functional groups enable its use in creating targeted drug delivery systems and prodrug formulations.
• Chemical Biology Probes: Utilized in the development of enzyme inhibitors and activity-based probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses serving the global pharmaceutical and biotech industries.

Basic Information

Item	Details
Product Name	2-Azetidinone,3-Amino-4-(2-Hydroxyethyl)-,(3S-Cis)-(9Ci)
CAS No.	115405-91-9
Molecular Formula	C5H10N2O2
Molecular Weight	130.15 g/mol
Synonyms	(3S,4R)-3-Amino-4-(2-hydroxyethyl)azetidin-2-one; 3-Amino-4-(2-hydroxyethyl)azetidin-2-one, (3S-cis)-; (3S,4R)-3-Amino-4-(2-hydroxyethyl)-2-azetidinone; cis-3-Amino-4-(2-hydroxyethyl)azetidin-2-one; L-3-Amino-4-(2-hydroxyethyl)azetidin-2-one; β-lactam intermediate 115405-91-9; Azetidinone derivative
EINECS	Contact for details

Quality Control

Our 2-Azetidinone,3-Amino-4-(2-Hydroxyethyl)-,(3S-Cis)-(9Ci) is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high stereochemical purity and chemical identity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, enantiomeric excess, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.