Description

3-Hydroxy-Polydeoxycholic Acid is a modified bile acid derivative with enhanced physicochemical properties, making it a valuable intermediate for advanced research and pharmaceutical development. Its significance lies in its role as a key building block for synthesizing novel drug candidates, particularly in the fields of metabolic and liver disease therapeutics. This high-purity compound is essential for pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) seeking to innovate in targeted drug delivery and metabolic pathway modulation.

Application

• Pharmaceutical Intermediate: A critical starting material or intermediate in the synthesis of novel therapeutic agents targeting metabolic disorders.
• Biochemical Research: Used as a reference standard or probe in studies investigating bile acid metabolism, liver function, and cellular signaling pathways.
• Drug Delivery Systems: Serves as a functional component in the development of advanced liposomal or micellar delivery systems to enhance drug solubility and bioavailability.
• API Development: Employed in the research and process development stages for creating new Active Pharmaceutical Ingredients (APIs) with improved efficacy profiles.
• Metabolic Pathway Studies: Utilized in in vitro and in vivo models to study the role of modified bile acids in cholesterol homeostasis and digestion.

Basic Information

Product Name	3-Hydroxy-Polydeoxycholic Acid
CAS No.	115349-14-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Polydeoxycholic Acid, 3-Hydroxy-; 3α-Hydroxy-5β-cholan-24-oic Acid Polymer; 3-Hydroxy Polydeoxycholate; Modified Deoxycholic Acid Polymer; Poly(3-hydroxydeoxycholic acid); 3-HPCA; 3-Hydroxy-PDCA
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-Polydeoxycholic Acid is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including chromatographic purity assays and structural confirmation. Certificates of Analysis (COA) documenting identity, purity, and related substances are provided and available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.