Description

20-Trifluoroarachidonicacid CAS NO 115178-89-7 is a fluorinated derivative of arachidonic acid, a key polyunsaturated fatty acid, where three hydrogen atoms are replaced by fluorine, significantly altering its biochemical properties and metabolic stability. This strategic fluorination makes it an invaluable tool compound for pharmaceutical research and advanced material science, offering enhanced resistance to enzymatic degradation. It is primarily utilized by researchers in medicinal chemistry for drug discovery and by specialty chemical manufacturers developing novel bioactive compounds and high-performance materials.

Application

• Medicinal Chemistry & Drug Discovery: Serves as a critical building block or probe for developing novel anti-inflammatory agents, enzyme inhibitors, and receptor modulators by leveraging its metabolic stability.
• Biochemical Research: Used as a stable analog in studies of eicosanoid pathways, lipid signaling, and cyclooxygenase (COX) or lipoxygenase (LOX) enzyme mechanisms.
• Pharmaceutical Intermediates: Acts as a key synthetic intermediate in the production of targeted therapeutic candidates, especially in areas of immunology and metabolic diseases.
• Specialty Material Synthesis: Employed in the synthesis of fluorinated polymers or advanced materials where the introduction of fluorine imparts desired properties like chemical resistance or thermal stability.
• Reference Standard: Provides a high-purity standard for analytical method development and validation in quality control laboratories.

Basic Information

Item	Detail
Product Name	20-Trifluoroarachidonicacid
CAS No.	115178-89-7
Molecular Formula	C₂₀H₂₉F₃O₂
Molecular Weight	358.44 g/mol
Synonyms	5,8,11,14-Eicosatetraenoic acid, 20,20,20-trifluoro-; 20,20,20-Trifluoroarachidonic Acid; 20-Trifluoro-5Z,8Z,11Z,14Z-eicosatetraenoic Acid; 20-Trifluoro-AA; TFAA; ω,ω,ω-Trifluoroarachidonic Acid; all-cis-5,8,11,14-Eicosatetraenoic acid, 20,20,20-trifluoro-
EINECS	Contact for details

Quality Control

Every batch of 20-Trifluoroarachidonicacid is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at -20°C or below to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.