Description

1-Acetyl-5-Nitroindolin-2-One is a high-purity, synthetically valuable nitro-substituted indolinone derivative. This compound serves as a critical pharmaceutical intermediate and versatile organic building block for advanced chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Organic Synthesis Reagent: Employed in academic and industrial research for constructing indole and indoline-based heterocyclic frameworks via nitro-group transformations.
• Material Science Precursor: Potential starting material for the synthesis of organic semiconductors, dyes, and photoactive compounds.

Basic Information

Product Name	1-Acetyl-5-Nitroindolin-2-One
CAS No.	114985-63-6
Molecular Formula	C10H8N2O4
Molecular Weight	220.18 g/mol
Synonyms	5-Nitro-1-acetylindolin-2-one; 1-Acetyl-5-nitro-2,3-dihydro-1H-indol-2-one; 2H-Indol-2-one, 1-acetyl-1,3-dihydro-5-nitro-; 5-Nitro-1-acetyl-2-indolinone; N-Acetyl-5-nitrooxindole; 5-Nitro-1-acetyl-2-oxindole; 1-Acetyl-5-nitrooxindole; 5-Nitro-2-oxo-1-acetylindoline
EINECS	Contact for details

Quality Control

Our 1-Acetyl-5-Nitroindolin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.