Description

Di-(8-Methylstearoyl)Phosphatidylcholine is a synthetic, chemically defined phospholipid derivative, specifically a phosphatidylcholine with branched-chain fatty acids. This structural modification offers enhanced stability and unique physicochemical properties compared to its linear-chain counterparts, making it a valuable component for advanced formulation development. It is primarily utilized in the pharmaceutical, cosmetic, and advanced material sectors where precise molecular control is critical for performance and reproducibility.

Application

• Pharmaceutical Excipient & Drug Delivery: As a key component in liposomal and lipid nanoparticle (LNP) formulations for targeted drug delivery, mRNA vaccines, and solubilizing poorly water-soluble APIs.
• Cosmetic Formulations: Used in high-end skincare products as an emulsifier, skin-conditioning agent, and to enhance the stability and skin penetration of active ingredients.
• Biomimetic Membrane Research: Serves as a model lipid in biophysical studies to investigate membrane fluidity, protein-lipid interactions, and the effects of branched lipids on bilayer structure.
• Diagnostic Reagents: Employed in the formulation of contrast agents and other diagnostic tools requiring stable, functionalized lipid layers.
• Advanced Material Science: A building block for creating functionalized surfaces, supported lipid bilayers (SLBs), and other nanostructured materials.

Basic Information

Product Name	Di-(8-Methylstearoyl)Phosphatidylcholine
CAS No.	114927-92-3
Molecular Formula	C46H92NO8P
Molecular Weight	818.20 g/mol
Synonyms	1,2-Di-(8-methylstearoyl)-sn-glycero-3-phosphocholine; Phosphatidylcholine, di(8-methylstearoyl)-; PC(18:0(8-Me)/18:0(8-Me)); Branched-chain phosphatidylcholine; Synthetic phospholipid 114927-92-3
EINECS	Contact for details

Quality Control

Our Di-(8-Methylstearoyl)Phosphatidylcholine is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white waxy solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Solubility	Soluble in chloroform, ethanol; insoluble in water
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.