Description

1-(2-Chloro-4-Nitrophenyl)-Piperazine is a versatile and high-value aromatic piperazine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and nitro substituents, makes it an essential intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antimicrobial research.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its aromatic heterocyclic core.
• Material Science: Acts as a monomer or functionalizing agent in the production of specialty polymers and dyes.
• Academic & R&D: Serves as a standard or starting material in university and corporate laboratories for methodological studies and novel reaction development.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to introduce the piperazine moiety into complex scaffolds.

Basic Information

Product Name	1-(2-Chloro-4-Nitrophenyl)-Piperazine
CAS No.	114878-60-3
Molecular Formula	C10H12ClN3O2
Molecular Weight	241.68 g/mol
Synonyms	2-Chloro-4-nitrophenylpiperazine; 1-(2-Chloro-4-nitrophenyl)piperazine; Piperazine, 1-(2-chloro-4-nitrophenyl)-; 2-Chloro-1-(4-nitrophenyl)piperazine; 4-Nitro-2-chlorophenylpiperazine; (2-Chloro-4-nitrophenyl)piperazine; 1-(2-Chloro-4-nitro-phenyl)-piperazine
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-4-Nitrophenyl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.