Description

Calcitonin, Salmon, Gly(8)-Ala(16)-Des-Leu(19)- is a synthetic analogue of salmon calcitonin, a polypeptide hormone. This modified sequence is engineered to enhance stability and biological activity, making it a critical active pharmaceutical ingredient (API) for therapeutic development. It is primarily required by pharmaceutical manufacturers and research institutions focused on metabolic bone disorders, such as osteoporosis and Paget's disease, as well as for pain management applications.

Application

• Active Pharmaceutical Ingredient (API) in injectable formulations for the treatment of osteoporosis.
• Key component in nasal spray formulations for postmenopausal osteoporosis and Paget's disease.
• Research and development of novel therapeutics for hypercalcemia and bone pain associated with malignancies.
• Biochemical research standard for studying calcium metabolism and osteoclast activity.
• Reference standard in quality control laboratories for assay validation and purity testing.
• Preclinical studies for evaluating the efficacy of calcitonin analogues.

Basic Information

Product Name	Calcitonin, Salmon, Gly(8)-Ala(16)-Des-Leu(19)-
CAS No.	114869-79-3
Molecular Formula	C₁₄₅H₂₄₀N₄₄O₄₈S₂
Molecular Weight	~3417.9 g/mol
Synonyms	Carbocalcitonin; Gly8,Ala16,Des-Leu19-Salmon Calcitonin; Salmon Calcitonin (8-32); Salmon Calcitonin Fragment 8-32; [Gly8,Ala16,Des-Leu19]-sCT; sCT(8-32); Calcitonin (salmon) (8-32) fragment; Calcitonin salmon (8-32)
EINECS	Contact for details

Quality Control

Our Calcitonin, Salmon, Gly(8)-Ala(16)-Des-Leu(19)- is manufactured under strict quality systems suitable for pharmaceutical development. Each batch undergoes comprehensive analytical testing including HPLC for purity and related substances, peptide content determination, and identity confirmation by mass spectrometry. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Single Maximum Impurity	≤ 1.0%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 5.0%
Biological Activity	Assayed; report provided

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.