Description

26-Iodoponasterone A is a chemically modified analog of the potent marine natural product ponasterone A, a member of the ecdysteroid class. This iodinated derivative is of significant interest in biochemical and pharmacological research due to its potential as a high-affinity ligand for ecdysone receptors and as a versatile synthetic intermediate. It is primarily utilized by research institutions, pharmaceutical R&D departments, and specialty chemical manufacturers focused on endocrinology, insect physiology, and novel therapeutic agent development.

Application

• Biochemical Research: Used as a molecular probe to study ecdysone receptor (EcR) signaling pathways and gene expression regulation in insect and mammalian cell systems.
• Pharmaceutical R&D: Serves as a key synthetic intermediate or a reference standard in the development of novel insect growth regulators and potential therapeutic agents.
• Endocrinology Studies: Employed in academic and industrial laboratories to investigate the structural-activity relationships (SAR) of ecdysteroids and their analogs.
• Agrochemical Development: Evaluated for its bioactivity in the creation of next-generation, selective insecticides that target specific hormonal pathways.
• Chemical Synthesis: Acts as a versatile building block for further chemical modifications, enabling the creation of a library of novel steroid-based compounds.

Basic Information

Product Name	26-Iodoponasterone A
CAS No.	114752-28-2
Molecular Formula	C27H41IO6
Molecular Weight	612.53 g/mol
Synonyms	26-Iodo-ponasterone A; 26-Iodoponasterone; 2β,3β,14α,20R,22R,25-Hexahydroxy-5β-cholest-7-en-6-one 26-iodo derivative; Ponasterone A 26-iodo analog; (20R,22R)-2β,3β,14α,20,22,25-Hexahydroxy-26-iodo-5β-cholest-7-en-6-one
EINECS	Contact for details

Quality Control

Our 26-Iodoponasterone A is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for advanced research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.