Description

1H-Imidazo[1,2-A]Indeno[1,2-E]Pyrazin-1-One, 5,5A,10,10A-Tetrahydro-8-Hydroxy-2-[(4-Hydroxyphenyl)Methyl]-4-(Phenylmethyl)- is a complex heterocyclic organic compound with a fused polycyclic structure, serving as a high-value advanced pharmaceutical intermediate and research chemical. Its unique molecular architecture makes it a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) and for advanced material science research. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Organic Synthesis Building Block: Used in complex multi-step organic synthesis for constructing fused heterocyclic systems with potential biological activity.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening in drug discovery programs.
• Biochemical Research: Potential tool compound for investigating enzyme inhibition and receptor binding mechanisms in academic and industrial research settings.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for advanced material applications.

Basic Information

Item	Details
Product Name	1H-Imidazo[1,2-A]Indeno[1,2-E]Pyrazin-1-One, 5,5A,10,10A-Tetrahydro-8-Hydroxy-2-[(4-Hydroxyphenyl)Methyl]-4-(Phenylmethyl)-
CAS No.	114540-25-9
Molecular Formula	C27H22N2O3
Molecular Weight	422.48 g/mol
Synonyms	5,5a,10,10a-Tetrahydro-8-hydroxy-2-[(4-hydroxyphenyl)methyl]-4-(phenylmethyl)-1H-imidazo[1,2-a]indeno[1,2-e]pyrazin-1-one; 1H-Imidazo[1,2-a]indeno[1,2-e]pyrazin-1-one, 5,5a,10,10a-tetrahydro-8-hydroxy-2-[(4-hydroxyphenyl)methyl]-4-(phenylmethyl)-; CAS 114540-25-9; 2-[(4-Hydroxybenzyl)]-4-benzyl-5,5a,10,10a-tetrahydro-8-hydroxy-1H-imidazo[1,2-a]indeno[1,2-e]pyrazin-1-one
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.