Description

(S)-3-Phenyl-2-[(Pyrazin-2-Ylcarbonyl)Amino] Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a chiral center and a pyrazine-based amide linkage. This compound serves as a critical pharmaceutical intermediate and chiral building block for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for applications in medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used to incorporate modified amino acid structures into peptide analogs to enhance stability, bioavailability, or receptor binding affinity.
• Protease Inhibitor Development: Serves as a core scaffold or side-chain component in the design of enzyme inhibitors targeting various proteases.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged compounds for studying biological pathways and protein interactions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective organic synthesis.
• Academic & Industrial R&D: Fundamental research tool in universities and corporate labs for exploring new chemical space and structure-activity relationships.

Basic Information

Product Name	(S)-3-Phenyl-2-[(Pyrazin-2-Ylcarbonyl)Amino] Propanoic Acid
CAS No.	114457-94-2
Molecular Formula	C14H13N3O3
Molecular Weight	271.27 g/mol
Synonyms	(S)-2-[(Pyrazine-2-carbonyl)amino]-3-phenylpropanoic acid; N-(Pyrazin-2-ylcarbonyl)-L-phenylalanine; L-Phenylalanine, N-(2-pyrazinylcarbonyl)-; (S)-N-(Pyrazine-2-carbonyl)phenylalanine; (S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid; 2-[(Pyrazin-2-ylcarbonyl)amino]-3-phenylpropanoic acid (S-enantiomer); CAS 114457-94-2
EINECS	Contact for details

Quality Control

Our (S)-3-Phenyl-2-[(Pyrazin-2-Ylcarbonyl)Amino] Propanoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.