Description

Piperazine, 2,5-Bis(1-Methylethyl)-, cis- (9Ci) is a specialized, substituted piperazine derivative characterized by its cis-configuration and isopropyl functional groups. This compound matters as a versatile chiral building block and intermediate, offering unique steric and electronic properties for advanced synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its structure can contribute to biological activity.
• Ligand and Catalyst Development: Acts as a precursor for creating chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial research applications.
• Academic and Industrial Research: A valuable tool for methodological studies in organic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Product Name	Piperazine, 2,5-Bis(1-Methylethyl)-, cis- (9Ci)
CAS No.	114420-44-9
Molecular Formula	C10H22N2
Molecular Weight	170.30 g/mol
Synonyms	cis-2,5-Diisopropylpiperazine; (2R,5S)-2,5-Diisopropylpiperazine; (2S,5R)-2,5-Diisopropylpiperazine; 2,5-Diisopropylpiperazine (cis-); cis-1,4-Diisopropyl-2,5-diazacyclohexane; NSC 405124; 2,5-Bis(1-methylethyl)piperazine (cis-); Piperazine, 2,5-diisopropyl-, cis-
EINECS	Contact for details

Quality Control

Our Piperazine, 2,5-Bis(1-Methylethyl)-, cis- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% cis-isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.