Description

1-o-Hexadec-1'-Enyl-2-Acetyl-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid derivative, specifically a platelet-activating factor (PAF) analog. This compound is of significant value for biochemical and pharmacological research due to its role as a potent bioactive lipid mediator. It is primarily needed by researchers and developers in the life sciences, pharmaceutical, and diagnostic industries for studying inflammatory responses, signal transduction pathways, and as a critical reference standard.

Application

• Biochemical Research: Used as a key agonist and reference standard in studies of platelet-activating factor (PAF) receptors and associated signaling cascades.
• Pharmaceutical Development: Serves as a critical tool compound for screening and developing PAF receptor antagonists for anti-inflammatory therapeutics.
• Cell Biology Studies: Employed to investigate cellular processes such as aggregation, degranulation, and oxidative burst in neutrophils and other immune cells.
• Diagnostic Reagent Manufacturing: Utilized in the formulation of specialized assay kits and calibration standards for inflammatory biomarker detection.
• Lipidomics & Metabolomics: Acts as a high-purity internal standard for the accurate quantification of PAF and related lipids in complex biological samples via LC-MS.
• Academic Research: Fundamental tool for universities and research institutes exploring the pathophysiology of asthma, anaphylaxis, and other inflammatory disorders.

Basic Information

Product Name	1-o-Hexadec-1'-Enyl-2-Acetyl-Sn-Glycero-3-Phosphocholine
CAS No.	114414-96-9
Molecular Formula	C26H52NO7P
Molecular Weight	521.67 g/mol
Synonyms	PAF C-16; 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine; Platelet-Activating Factor C-16; Hexadecyl PAF; AGEPC (1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine); AGEPC C-16:0; 1-O-Hexadecyl-2-acetyl-GPC; sn-Glycero-3-phosphocholine, 1-O-hexadecyl-2-acetyl-
EINECS	Contact for details

Quality Control

Our 1-o-Hexadec-1'-Enyl-2-Acetyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic and moisture-sensitive; allow the vial to equilibrate to room temperature in a desiccator before opening to minimize water absorption.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (by weight)	≥ 98%
Solubility	Soluble in chloroform, methanol, ethanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.