Description

Piperazine, 2,5-Bis(1-Methylethyl)-, (2S-Cis)- (9Ci) is a high-purity, stereochemically defined piperazine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a chiral intermediate, enabling the production of enantiomerically pure compounds with specific biological activities. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those developing novel active pharmaceutical ingredients (APIs) and crop protection agents. The CAS number for this compound is 114409-91-5.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is required for optimal efficacy and environmental profile.
• Catalyst Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis, such as hydrogenation or cross-coupling reactions.
• Fine Chemical Research: Employed in academic and industrial R&D for constructing complex nitrogen-containing heterocycles and exploring new chemical spaces.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Item	Detail
Product Name	Piperazine, 2,5-Bis(1-Methylethyl)-, (2S-Cis)- (9Ci)
CAS No.	114409-91-5
Molecular Formula	C10H22N2
Molecular Weight	170.30 g/mol
Synonyms	(2S,5S)-2,5-Diisopropylpiperazine; cis-2,5-Diisopropylpiperazine; (2S-cis)-2,5-Bis(1-methylethyl)piperazine; 2,5-Diisopropylpiperazine, (2S,5S)-; L-(+)-2,5-Diisopropylpiperazine; (2S,5S)-2,5-DIP; cis-(2S,5S)-2,5-Diisopropylpiperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 2,5-Bis(1-Methylethyl)-, (2S-Cis)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.