Description

1-Benzyl-5-Oxopyrrolidine-3-Carbonyl Chloride is a high-purity organic intermediate featuring a reactive acid chloride group and a protected pyrrolidone scaffold. This compound matters as a versatile building block for the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological disorders or acting as enzyme inhibitors.
• Peptidomimetic Synthesis: Used in the construction of peptidomimetics and constrained amino acid analogs due to its pyrrolidone backbone.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, or plant growth regulators.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis or metal complexation.
• Polymer Modification: Can be used to introduce functional groups into polymer chains for specialty material applications.
• Chemical Biology Probes: Useful for synthesizing activity-based probes or labeled compounds for biochemical studies.

Basic Information

Product Name	1-Benzyl-5-Oxopyrrolidine-3-Carbonyl Chloride
CAS No.	114368-05-7
Molecular Formula	C13H14ClNO2
Molecular Weight	251.71 g/mol
Synonyms	1-Benzyl-5-oxopyrrolidine-3-carbonyl chloride; 3-(Chlorocarbonyl)-1-benzyl-2-pyrrolidinone; 1-Benzyl-3-(chlorocarbonyl)-2-pyrrolidinone; 1-Benzylpyrrolidine-3-carbonyl chloride, 5-oxo-; 2-Pyrrolidinone, 3-(chlorocarbonyl)-1-(phenylmethyl)-; 3-Carbamoyl-1-benzylpyrrolidin-2-one chloride
EINECS	Contact for details

Quality Control

Our 1-Benzyl-5-Oxopyrrolidine-3-Carbonyl Chloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.